I am Yinda Chen (陈胤达), a Ph.D. candidate jointly trained by the University of Science and Technology of China (USTC) and the Shanghai AI Lab, majoring in Information and Communication Engineering.
-
👀 My research focuses on multimodal understanding and generation. Initially, I explored these two directions separately—working on representation learning, self-supervised pretraining, and efficient fine-tuning in biomedical image processing and other multimodal tasks. Now, I’m gradually moving toward a unified framework that bridges understanding and generation across various domains.
-
🧭 I have the immense privilege of being advised by Prof. Feng Wu (吴枫, IEEE Fellow) and Prof. Zhiwei Xiong (熊志伟) at USTC, and working under the collaborative supervision of Prof. Xiaoou Tang (汤晓鸥, IEEE Fellow) at the Shanghai AI Lab. I also have the honor to collaborate closely with Prof. Dong Liu (刘东), Prof. Li Li (李礼), and Prof. Zhihai He (何志海, IEEE Fellow). Additionally, I’ve been fortunate to conduct research internships at Imperial College London with Dr. Rossella Arcucci and Dr. Che Liu (刘澈), and the PLA General Hospital (301 Hospital) with Academician Qionghai Dai (戴琼海, IEEE Fellow).
-
🌱 Currently, I’m an intern at Tencent IEG (Interactive Entertainment Group) through the Qingyun Program, working on TTS (Text-to-Speech) generation and multimodal understanding for Honor of Kings – Lingbao projects under the guidance of Dr. Liang Du (杜量) and Dr. Wentao Yao (姚文韬), exploring how generation and understanding can work hand in hand.
-
💞️ Coming from a non-traditional background with dual bachelor’s degrees in Environmental Ecological Engineering and Economics at Xiamen University, I’ve always been fascinated by interdisciplinary research. During my undergraduate years, I had the privilege of being mentored by Prof. Yuanye Zhang (张原野), whose passion and rigor guided me into my initial research endeavors. My journey into AI began in 2021 as an active member of WISERCLUB, a data science community that shaped my early curiosity—I’m deeply grateful to my good friend Ziqian Lin (林子谦) (now at Peking University Guanghua School of Management, Department of Statistics) for recommending me to this amazing community. As someone who transitioned across fields, I deeply understand the challenges of learning something entirely new, and this experience has made me incredibly grateful for every mentor and collaborator who has guided me along the way.
-
📝 Thanks to the generous guidance of my mentors and the support of amazing collaborators, I’ve been fortunate to publish papers
at conferences including AAAI, NeurIPS, MICCAI, ICCV, and IJCAI.
I know my talents may not match those of many brilliant pioneers in this field, but I believe in the power of continuous learning and genuine collaboration. I’m always eager to exchange ideas, seek advice from the community, and help those who are just starting their research journey. Please feel free to reach out—I’d be truly honored to connect, collaborate, or simply share thoughts about research! 🌟
🔥 News
- 2025.10.16 One paper was accepted by JBHI (IEEE Journal of Biomedical and Health Informatics).
- 2025.08 Started as Qingyun intern at Tencent IEG, working on game video scene understanding.
- 2025.06.26 One paper was accepted by ICCV 2025.
- 2025.05.15 One paper was accepted by ACL 2025 findings.
- 2025.05.01 One paper was accepted by ICML 2025.
- 2025.01.18 One paper was selected as oral by AAAI 2025.
- 2024.12.06 I was successfully selected as the principal investigator of the Ph.D. Natural Science Foundation Project.
- 2024.10.10 One paper was accepted by NeurIPS 2024.
- 2024.06.18 Two papers were accepted by MICCAI 2024.
📖 Education
-
University of Science and Technology of China & Shanghai AI Lab
Ph.D. in Information and Communication Engineering (Expected 2027)
📍 Hefei & Shanghai · Sept 2024 - Present
- Research focus: Machine Learning Theory, Self-Supervised Pretraining, Multimodal Large Models, Image Coding & Compression
- Working with Prof. Feng Wu (IEEE Fellow) and Prof. Zhiwei Xiong
- Research collaboration with Prof. Xiaoou Tang (IEEE Fellow) at Shanghai AI Lab
- Selected coursework: Algorithm Design and Analysis, Statistical Learning, Deep Learning, Reinforcement Learning
- Principal Investigator for NSFC Ph.D. Project (2024)
-
University of Science and Technology of China
M.S. in Computer Technology
📍 Hefei · Sept 2022 - July 2024
- Recipient of National Graduate Scholarship (2022)
-
Xiamen University
B.S. in Environmental Ecological Engineering & Economics (Dual Degree)
📍 Xiamen · Sept 2018 - July 2022
- Academic ranking: 1st/31 overall
- Xiamen University Academic Star (2021), CDA Level 1 Certification (2022), Kaggle Expert
- Research advisor: Prof. Yuanye Zhang
💼 Professional Experience
-
Tencent Interactive Entertainment Group (IEG)
Qingyun Program Intern
📍 Shanghai · Aug 2025 - Present
- Developing TTS (Text-to-Speech) systems and multimodal scene understanding for Honor of Kings – Lingbao and League of Legends highlight commentary
- Supervised by Dr. Liang Du and Dr. Wentao Yao
- Designed TTS models for generating game commentary and character voiceovers, exploring generation-understanding synergy
- Developed multimodal algorithms to analyze game video content and automatically generate contextual commentary scripts
-
Chinese PLA General Hospital (301 Hospital)
Research Intern, Data Compression Group
📍 Beijing · Sept 2023 - Feb 2024
- Collaborated with Academician Qionghai Dai’s team on efficient data compression research
- Designed medical image-specific compression algorithms for CT, MRI, and other modalities
- Achieved 35% improvement in compression efficiency
-
Research Intern, Data Science Institute
📍 London (Remote) · Nov 2022 - Aug 2023
- Collaborated with Dr. Rossella Arcucci and Dr. Che Liu on multimodal pretraining research
- Developed image-text contrastive learning framework achieving 93.5% accuracy on medical diagnosis tasks
- Submitted one journal paper
-
- Designed and led data mining courses, delivering lectures on clustering and Transformer architectures
- Mentored 20 undergraduate students in machine learning projects and organized 2 campus-wide competitions
- Media coverage
-
Wang Yanan Institute for Studies in Economics, Xiamen University
Research Assistant, Econometrics
📍 Xiamen · Aug 2020 - Dec 2021
- Assisted Associate Prof. Jiong Zhu in national land economic statistics research
- Conducted visual feature extraction for homestead information and land use analysis
- Developed satellite imagery analysis tools achieving 85% accuracy in identifying land use changes
📝 Selected Publications
For a complete list of publications, please visit my Google Scholar profile
Note: * denotes equal contribution
📰 Journal Articles

EMPOWER: Evolutionary Medical Prompt Optimization With Reinforcement Learning
IEEE Journal of Biomedical and Health Informatics | October 16, 2025
Yinda Chen*; Yangfan He*; Jing Yang; Dapeng Zhang; Zhenlong Yuan; Muhammad Attique Khan; Jamel Baili; Por Lip Yee
EMPOWER proposes an evolutionary framework for medical prompt optimization through specialized representation learning and multi-dimensional evaluation. It achieves 24.7% reduction in factual errors and 15.3% higher clinician preference.

Unsupervised Domain Adaptation for EM Image Denoising with Invertible Networks
IEEE Transactions on Medical Imaging | July 29, 2024
Shiyu Deng; Yinda Chen; Wei Huang; Ruobing Zhang; Zhiwei Xiong
The paper proposes an unsupervised domain adaptation method for EM image denoising with invertible networks, outperforming existing methods.
🎓 Conference Papers

TokenUnify: Scaling Up Autoregressive Pretraining for Neuron Segmentation
ICCV | October 25, 2025
Yinda Chen*; Haoyuan Shi*; Xiaoyu Liu; Te Shi; Ruobing Zhang; Dong Liu; Zhiwei Xiong; Feng Wu
| Code |
Dataset |
Weights |
TokenUnify proposes a hierarchical predictive coding framework for neuron segmentation, reducing autoregressive error from O(K) to O(√K). It introduces a dataset with 1.2 billion annotated voxels and achieves 44% improvement over training from scratch.

MaskTwins: Dual-form Complementary Masking for Domain-Adaptive Image Segmentation
ICML | July 13, 2025
Jiawen Wang; Yinda Chen* (Theory Contribution & Project Leader); Xiaoyu Liu; Che Liu; Dong Liu; Jianqing Gao; Zhiwei Xiong
| Code |
Poster |
MaskTwins introduces a dual-form complementary masking strategy for domain-adaptive image segmentation, effectively bridging the domain gap through coordinated spatial and feature-level masking mechanisms.

Condition-generation Latent Coding with an External Dictionary for Deep Image Compression
AAAI (oral) | March 06, 2025
Siqi Wu; Yinda Chen*; Dong Liu; Zhihai He
| Code |
Weights |
The paper proposes CLC for deep image compression. It uses a dictionary to generate references, shows good performance, and has theoretical analysis.

MaskFactory: Towards High-quality Synthetic Data Generation for Dichotomous Image Segmentation
NeurIPS | October 17, 2024
Haotian Qian; Yinda Chen*; Shengtao Lou; Fahad Shahbaz Khan; Xiaogang Jin; Deng-Ping Fan
| Project | Code |
MaskFactory proposes a two-stage method to generate high-quality synthetic datasets for DIS, outperforming existing methods in quality and efficiency.

BIMCV-R: A Landmark Dataset for 3D CT Text-Image Retrieval
MICCAI | October 06, 2024
Yinda Chen; Che Liu; Xiaoyu Liu; Rossella Arcucci; Zhiwei Xiong
This paper presents BIMCV-R, a 3D CT text-image retrieval dataset, and MedFinder. Tests show MedFinder outperforms baselines in related tasks.

Learning multiscale consistency for self-supervised electron microscopy instance segmentation
ICASSP | April 13, 2024
Yinda Chen; Wei Huang; Xiaoyu Liu; Shiyu Deng; Qi Chen; Zhiwei Xiong
A pretraining framework for EM volume instance segmentation is proposed. It enforces multiscale consistency and shows good performance in neuron and mitochondria segmentation.

Self-Supervised Neuron Segmentation with Multi-Agent Reinforcement Learning
IJCAI (oral) | August 17, 2023
Yinda Chen; Wei Huang; Shenglong Zhou; Qi Chen; Zhiwei Xiong
| Code |
Pretrain Data |
CREMI | VNC |
This paper proposes a decision-based MIM for neuron segmentation in EM data. It uses MARL to optimize masking, outperforming alternatives.
🥇 Honors and Awards
- 🎓 National Natural Science Foundation of China (NSFC) PhD Program (December 2024)
- Role: Principal Investigator
- Achievement: Sole awardee in Information Science, Anhui Province
- Description: Prestigious national research funding program for doctoral students
- 🏆 Interdisciplinary Contest in Modeling (ICM), Outstanding Winner (May 2024)
- Competition: International mathematical modeling competition organized by COMAP
- Ranking: Top 0.17% of 10,388 participating teams worldwide
- Resources: 📝 Paper & Code
- 🎓 National Graduate Scholarship (December 2022)
- Achievement: National award for academic performance and research contributions (Top 1%)
- Reference: 🔗 Official Announcement
- 🎓 Xiamen University Academic Star (December 2021)
- Achievement: Sole undergraduate awardee university-wide
- Recognition: Outstanding academic achievements and research excellence
-
Media: 🔗 University News Feature Report
- 🏆 “Jingrun Cup” Mathematics Competition (Professional Category), First Prize (September 2021)
- Level: Campus-level competition named after renowned mathematician Chen Jingrun
- Ranking: University First Place
- Reference: 🔗 Competition News
- 🏆 “Internet+” Innovation and Entrepreneurship Competition, Gold Medal (August 2021)
- Level: Provincial level competition
- Region: Fujian Province
- 🏆 National Undergraduate Mathematics Competition (Non-Major Category), Second Prize (May 2021)
- Competition: National finals organized by the Chinese Mathematical Society
- Progress: Advanced from provincial first place
- Reference: 🔗 Competition News
- 🏆 “Challenge Cup” National Undergraduate Academic Science and Technology Competition, First Prize (May 2021)
- Level: Provincial level competition
- Region: Fujian Province
- 🏆 National Undergraduate Mathematics Competition (Non-Major Category), First Prize (November 2020)
- Competition: High-level national mathematics competition for undergraduate students
- Ranking: Provincial First Place, Fujian Province
💬 Talks and Teaching
- 2023.03, JD Medical Team, Talk on Medical Pretraining Using Generative Methods
Delivered a talk on the application of generative methods in vision-language models (VLMs) for medical pretraining. The presentation focused on leveraging advanced generative techniques to enhance performance in medical AI tasks - 2021.08, XMU Wiserclub–Data Mining Xiamen University, WISER Club
Responsible for designing and discussing the Data Mining course. Delivered lectures on Clustering and Feature Extraction topics.
💻 Skills
- 💻 Programming Languages: Python, C++, MATLAB, Mathmatica
- 🧠 Deep Learning Frameworks: TensorFlow, PyTorch
- 📊 Data Analysis: Pandas, NumPy
- 🌐 Web Development: HTML, CSS, JavaScript, Vue
- 🛠️ Tools: Git, Docker
🎓 Professional Service
I have served as a reviewer for prestigious conferences and journals, including:
- Computer Vision: CVPR, ICCV, WACV
- Machine Learning & AI: NeurIPS, ICML, ICLR, AAAI, AISTATS
- Medical Imaging & Multimedia: MICCAI, ACM MM
- Journals: IJCV, TIP
🎯 Hobbies & Interests
- 🎤 Singing: Love belting out tunes and exploring different music styles
- 🍳 Cooking: Always experimenting with new recipes - my kitchen is my lab!
- 🏸 Sports: Into badminton, basketball, and table tennis. Also hitting the gym as a total newbie (don’t judge!)
- 🎲 Board Games: Obsessed with strategy games like Splendor (璀璨宝石), Catan (卡坦岛), Ticket to Ride (车票之旅), Azul (花砖物语), 7 Wonders (世界七大奇迹), Carcassonne (卡卡颂), and Wingspan (展翅翱翔). Game night anyone?
- ⛰️ Hiking & Traveling: Love chasing sunrises on mountain peaks and getting lost in new cities. Recently explored the misty heights of Huangshan, the sacred temples of Jiuhuashan, wandered through Zhuhai’s coastlines and Changsha’s food scene. Been lucky enough to haggle in Istanbul’s bazaars, ride camels in Morocco’s Sahara, and get caffeinated in Seoul’s trendy streets
- 🎮 Gaming: Not just building Honor of Kings (Lingbao Project developer here!) but also crushing it as a player - rocking National Server Nezha, Golden Badge Nakoruru, and ranked Top 50 Jungler in Hefei. Let’s duo queue sometime!
Feel free to hit me up for karaoke sessions, board games, badminton matches, hiking trips, or just grabbing food and chatting about life! Always down to meet cool people and try new things 🎉
📬 Let’s Connect
- 📫 You can reach out to me via email at cyd0806@mail.ustc.edu.cn.
- 💼 I’m eager to connect with fellow deep learning enthusiasts and graduate researchers who share similar interests and are passionate about advancing the frontiers of AI in these domains.
- 📍 USTC Gaoxin campus, Hefei, Anhui, China
Feel free to drop me an email to discuss potential collaborations, share your ideas, or just have a friendly chat!